The Potential Therapeutic Effect of Orexin-Treated versus Orexin-Untreated Adipose Tissue-Derived Mesenchymal Stem Cell Therapy on Insulin Resistance in Type 2 Diabetic Rats
Type 2 diabetes mellitus is a chronic metabolic disease characterized by resistance to peripheral insulin actions.Mesenchymal stem cells have been studied for years in T2DM therapy, including adipose tissue-derived mesenchymal stem cells (AD-MSCs).Orexin neuropeptides (A and B) are well-known regulators of appetite and physical activity.The aim of